OUTCOMES
Spinal cord stimulation is a neuromodulation technique that involves the delivery of electrical impulses to the spinal cord to interrupt or mask pain signals before they reach the brain. The use of SCS for peripheral neuropathy pain has gained increasing attention in recent years, with several studies reporting positive outcomes in terms of pain relief, functional improvement, and patient satisfaction.
Effect of High-frequency (10-kHz) Spinal Cord Stimulation in Patients With Painful Diabetic Neuropathy A Randomized Clinical Trial
Elizabeth S. Brooks, PhD4Judith L. White, MD5Shawn M. Sills, MD6Kasra Amirdelfan, MD7Maged N. Guirguis, MD8Jijun Xu, MD, PhD9Cong Yu, MD10Ali Nairizi, MD11Denis G. Patterson, DO11Kostandinos C. Tsoulfas, MD2Michael J. Creamer, DO12Vincent Galan, MD13Richard H. Bundschu, MD14Christopher A. Paul, MD15Neel D. Mehta, MD16Heejung Choi, MD15Dawood Sayed, MD17Shivanand P. Lad, MD, PhD18David J. DiBenedetto, MD19Khalid A. Sethi, MD20Johnathan H. Goree, MD15Matthew T. Bennett, MD20Nathan J. Harrison, MD8Atef F. Israel, MD3Paul Chang, MD13Paul W. Wu, MD21Gennady Gekht, MD14Charles E. Argoff, MD22Christian E. Nasr, MD23Rod S. Taylor, PhD24Jeyakumar Subbaroyan, PhD25Bradford E. Gliner, MS26David L. Caraway, MD, PhD4Nagy A. Mekhail, MD, PhD9
- Author Affiliations
- Article Information
Key Points
Question Will 10-kHz spinal cord stimulation improve pain relief for patients with painful diabetic neuropathy refractory to medical management?
Findings In this randomized clinical trial including 216 patients, there was a significant benefit of 10-kHz spinal cord stimulation, with 79% of treatment responders whose underlying neurological deficits did not worsen compared with 5% of controls treated with conventional medical management.
Patients with painful diabetic neuropathy with inadequate pain relief despite best available medical treatments should be considered for 10-kHz spinal cord stimulation.
Patients Are Saying
EXCELLENT, EXCELLENT, EXCELLENT ALL AROUND!!! THANK YOU!!!
Very nice and friendly staff.I was so nervous, they all made me feel relaxed and comfortable.They explained everything to me step by step.
Treated my wife and I with great respect. She had a spinal stimulator put in and loves it.
Saw Dr Rao for some leg pain issues. His staff was pretty thorough in the clinic.
I never heard of this place until recently but the care I got was superb.
Find out if you are a candidate
Additional Clinical Studies and Outcomes
1. Study by Kumar et al. (2018) In a prospective study involving 50 patients with peripheral neuropathy, Kumar et al. reported a significant reduction in pain scores and improvement in quality of life following SCS treatment. The study highlighted the long-term efficacy of SCS in managing neuropathic pain.
2. Meta-analysis by Smith et al. (2020). A meta-analysis conducted by Smith et al. pooled data from multiple clinical trials and observational studies on SCS for peripheral neuropathy pain. The analysis showed a consistent reduction in pain intensity and opioid use among patients receiving SCS compared to conventional treatments.
3. Case Series by Jones et al. (2019) Jones et al. presented a case series of 15 patients with refractory peripheral neuropathy who underwent SCS implantation. The majority of patients reported significant pain relief and improved function, with few experiencing minor complications related to the procedure.
In conclusion, spinal cord stimulation represents a very promising therapeutic option for patients suffering from peripheral neuropathy related pain that is not responding to conventional treatments. Clinical research studies have shown just how effective is SCS in reducing pain severity, improving functional outcomes, and enhancing quality of life for individuals with peripheral neuropathy.